Marburg Virus Disease Outbreak: Causes, Symptoms, and Treatments

Marburg virus illness is a highly and severe fatal disease. Ebola virus and Marburg virus are relatively similar because they came from the same family. Are you aware that these two viruses are one of the most infectious pathogens that infect humans? Yes, it is true and now that you are already aware, let me remind you that both of them are uncommon diseases. And on the other hand, these two have the capability to cause vivid epidemics with a high casualty.
In fact, this extreme and severe fatal disease was first recognized in 1967. And unfortunately, there are two big outbreaks that happened simultaneously in Belgrade, Serbia and in Frankfurt and Marburg in Germany. Afterwards, sporadic cases and outbreaks have been testified in South Africa, Kenya, the Democratic Republic of the Congo, and Angola. And this year 2017 Marburg virus also infected Uganda.
Marburg virus continues to develop in Eastern Uganda, Kween District to be exact. That is why frontline health workers who are bathing this fatal disease have been commended to encourage local capacity. On the other hand, this emergency response is a great way to solve the present and yet to come outbreaks.
According to Dr. Zabulon Yoti, of World Health Organization (WHO) that community commitment is the foundation of emergency response.

Causes of Marburg Virus

In the beginning, contamination with Marburg virus results from caves populated by Rousettus bat groups. Or from continued contact with mines. Also, Marburg spread over human-to-human communication through direct contact (via mucous membranes or broken skin).

Symptoms of Marburg Virus

The development period (interval time from contamination to start of symptoms) differs from two to twenty-one days. Illness triggered by Marburg activates shortly with
• Severe headache
• Severe malaise
• High fever
• Muscle pains and aches
• Severe watery diarrhea
• Abdominal cramping and pain, nausea, vomiting for the first three days.
So when you are experiencing these symptoms it is better to talk or consult your doctor immediately for your safety. Moreover, the physical look of patients who are infected by Marburg virus has been defined as viewing “ghost-like” features. In addition to this are expressionless faces, extreme lethargy, and deep-set eyes.
Furthermore, patients who suffering Marburg for more than 5 days may possibly experience severe hemorrhagic signs. And sometime fatal cases may experience severe bleeding from several areas such as vagina, gums, and nose.

Diagnosis

Distinguishing Marburg virus disease from other contagious illness such as meningitis, typhoid fever, malaria, and shigellosis is difficult. However, medical experts used several diagnostic methods in order confirm the different symptoms of this virus. Here are the following:
• Antibody ELISA (Enzyme-linked Immunosorbent Assay)
• Serum Neutralization Test
• Antigen Detection Test
• RT-PCR (Reverse-transcriptase Polymerase Chain Reaction)
• Virus isolation
Furthermore, samples collected from Marburg virus patients are dangerous biohazard danger. So that non-activated examples and laboratory testing must be accompanied by extreme biological containment situations.

Treatment for Marburg Virus

• Rehydration with intravenous or oral fluids and
• Supportive care
However, there is still no proven available treatment for this fatal disease. Although, numerous possible treatments such as drug therapies, immune therapies, and blood products are presently being evaluated.

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